Comparison of the effects in vitro of tea tree oil and plaunotol on methicillin-susceptible and methicillin-resistant strains of Staphylococcus aureus

Citation
T. Hada et al., Comparison of the effects in vitro of tea tree oil and plaunotol on methicillin-susceptible and methicillin-resistant strains of Staphylococcus aureus, MICROBIOS, 106, 2001, pp. 133-141
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
MICROBIOS
ISSN journal
0026-2633 → ACNP
Volume
106
Year of publication
2001
Supplement
2
Pages
133 - 141
Database
ISI
SICI code
0026-2633(2001)106:<133:COTEIV>2.0.ZU;2-A
Abstract
The effects in vitro of tea tree oil (TTO) and plaunotol were examined by m onitoring the growth of a standard strain of Staphylococcus aureus FDA 209P and of fourteen methicillin-susceptible strains of S. aureus (MSSA), toget her with twenty methicillin-resistant strains (MRSA). The minimum inhibitor y concentrations (MIC) and the doses for 50% inhibition of growth (ID50) we re determined by the micro-broth dilution (MD) method, and the broth diluti on with shaking (BDS) method, respectively. The MIC of plaunotol for 50 and 90% of the MSSA and MRSA were assessed by the MID method, as 16 mug/ml and 1,024 mug/ml, respectively. No antibacterial effects of TTO on MSSA and MR SA were detected by the MID method. The growth-inhibitory effects of TTO on S. aureus by the BIDS method were examined, and it appeared that TTO was e ffective over a lower range of concentrations than previously reported. It seems that TTO is very effective in vitro against MSSA and MRSA at high con centrations but less effective below 40 mug/ml of TTO.