Zucker obese rats are sensitive to weight-reducing effect and insensitive to orexigenic effect by cold exposure

Citation
S. Hori et al., Zucker obese rats are sensitive to weight-reducing effect and insensitive to orexigenic effect by cold exposure, J THERM BIO, 26(4-5), 2001, pp. 479-483
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Animal Sciences",Physiology
Journal title
JOURNAL OF THERMAL BIOLOGY
ISSN journal
0306-4565 → ACNP
Volume
26
Issue
4-5
Year of publication
2001
Pages
479 - 483
Database
ISI
SICI code
0306-4565(200109)26:4-5<479:ZORAST>2.0.ZU;2-5
Abstract
Male Wistar and Zucker (lean and obese) rats at 7 weeks of age were divided into three groups: warm-acclimated (25 degreesC for 11 weeks), cold-acclim ated (10 degreesC for 11 weeks), and deacclimated (10 degreesC for 9 weeks and 25 degreesC for 2 weeks) groups. The rate of increase in body mass (BM) was lower in obese rats as compared to lean rats. Cold-acclimated Wistar a nd Zucker lean rats exhibited greater food intake, compared to warm-acclima ted rats. Food intake did not increase in obese rats exposed to cold. Obese rats are sensitive to weight-reducing effect and insensitive to the orexig enic effect by cold exposure. (C) 2001 Elsevier Science Ltd. All rights res erved.