Effects of smoking on myocardial injury in patients with conservatively treated acute myocardial infarction - A study with resting I-123-15-iodophenyl 3-methyl pentadecanoic acid/Tl-201 myocardial single photon emission computed tomography
H. Yamagishi et al., Effects of smoking on myocardial injury in patients with conservatively treated acute myocardial infarction - A study with resting I-123-15-iodophenyl 3-methyl pentadecanoic acid/Tl-201 myocardial single photon emission computed tomography, JPN CIRC J, 65(9), 2001, pp. 769-774
Citations number
38
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Many reports have demonstrated that smokers who have suffered an acute myoc
ardial infarction (AMI) have a better prognosis than nonsmokers. The presen
t study investigated the effects of current smoking on myocardial injury wi
th resting I-123-15-iodophenyl 3-methyl pentadecanoic acid (BMIPP)/Tl-201 m
yocardial single photon emission computed tomography in 103 patients with c
onservatively treated AMI. The left ventricular myocardium was divided into
9 segments and BMIPP and 201TI defects were scored using a 5-point grading
system (0=normal and 4=no uptake). The sum of the defect scores was define
d as the total defect score. There was no significant difference in either
the baseline severity of the coronary artery disease or the total defect sc
ores for BMIPP and Tl-201 between the current smoker and nonsmoker groups.
The difference between the total defect scores for BMIPP and Tl-201 tended
to be larger in the current smoker group than in the nonsmoker group (2.0 /-1.9 vs 1.3 1.6, p=0.056). Forty-one (53%) of 77 patients in the current s
moker group exhibited a BMIPP/Tl-201 mismatch, whereas only 8 (31%) of 26 p
atients in the nonsmoker group did (p=0.047). In conclusion, current smoker
s had more likelihood of salvageable myocardium in areas at risk, as demons
trated by BMIPP/Tl-201 mismatch, in AMI than nonsmokers.