Colonic transit disorders in systemic sclerosis

Citation
Sj. Wang et al., Colonic transit disorders in systemic sclerosis, CLIN RHEUMA, 20(4), 2001, pp. 251-254
Citations number
22
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Rheumatology
Journal title
CLINICAL RHEUMATOLOGY
ISSN journal
0770-3198 → ACNP
Volume
20
Issue
4
Year of publication
2001
Pages
251 - 254
Database
ISI
SICI code
0770-3198(2001)20:4<251:CTDISS>2.0.ZU;2-E
Abstract
Systemic sclerosis (SS) alters smooth muscle function throughout the gastro intestinal tract, the oesophagus being the segment most often involved. Inv olvement of the colon, though less common, may lead to life-threatening com plications. We studied 23 unselected patients with SS and 20 age-matched he althy controls using radionuclide colon transit studies. The geometric cent re (GC) at 4 and 24 hours was used to summarise overall transit in the colo n. In patients with SS, colon transit was delayed (GC(4): 0.39 +/- 0.36 vs 0.85 +/- 0.45; P=0.001) (GC(24): 1.68 +/- 0.9 vs 2.58 +/- 1.08; P=0.006). T hese findings suggest that delayed colon transit is common in patients with SS.