Selective reduction of aldehydes via BINOL-Zr complex

Citation
M. Lorca et al., Selective reduction of aldehydes via BINOL-Zr complex, TETRAHEDR L, 42(36), 2001, pp. 6243-6246
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
0040-4039 → ACNP
Volume
42
Issue
36
Year of publication
2001
Pages
6243 - 6246
Database
ISI
SICI code
0040-4039(20010903)42:36<6243:SROAVB>2.0.ZU;2-O
Abstract
An easily assembled catalyst from (+/-)-BINOL (1,1 ' -bi-naphthol) and Zr(O ' Pr)(4). ' PrOH selectively reduces aldehydes at room temperature. Ketone s remain intact under these conditions. A catalytic amount of BINOL-Zr comp lex in the presence of 2-propanol also effectively reduces a variety of chi ral and achiral aldehydes. (C) 2001 Published by Elsevier Science Ltd.