Clinical features of multiple sclerosis in a genetically homogeneous tropical population

Citation
Jl. Sanchez et al., Clinical features of multiple sclerosis in a genetically homogeneous tropical population, MULT SCLER, 7(4), 2001, pp. 227-229
Citations number
13
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
MULTIPLE SCLEROSIS
ISSN journal
1352-4585 → ACNP
Volume
7
Issue
4
Year of publication
2001
Pages
227 - 229
Database
ISI
SICI code
1352-4585(200108)7:4<227:CFOMSI>2.0.ZU;2-S
Abstract
Individuals affected with multiple sclerosis (MS) from a genetically homoge neous Caucasian population in Antioquia, a tropical region of Colombia, wer e evaluated in order to observe the clinical behavior of the disease. The f requency of clinical manifestations in 65 patients with definite MS from An tioquia was compared with those reported from temperate regions. The most c ommon manifestations were optic neuritis and motor symptoms with absence of cerebellar symptoms. This presentation is significantly different from the frequency distribution at onset in series from temperate regions. These di fferences suggest that environmental factors could modify the clinical expr ession of MS in this population.