Increasing body fat mass in the first year of hemodialysis

Citation
E. Ishimura et al., Increasing body fat mass in the first year of hemodialysis, J AM S NEPH, 12(9), 2001, pp. 1921-1926
Citations number
35
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Urology & Nephrology","da verificare
Journal title
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
ISSN journal
1046-6673 → ACNP
Volume
12
Issue
9
Year of publication
2001
Pages
1921 - 1926
Database
ISI
SICI code
1046-6673(200109)12:9<1921:IBFMIT>2.0.ZU;2-T
Abstract
Nutritional status affects well-being and survival in patients who are unde rgoing hemodialysis. It was examined how maintenance hemodialysis altered b ody fat mass. In 72 patients with chronic renal failure (age, 62 +/- 12 yr; 42 men, 30 women), body fat was measured by dual x-ray absorptiometry 1 mo after initiation of maintenance hemodialysis and approximately I yr later (mean +/- SD, 11 +/-2 mo). The second measurement showed significantly grea ter body fat mass than the first (11.38 +/-3.84 verstis 10.09 +/-4.12 kg; P <0.0001). After calculation of the change in body fat mass per month, no si gnificant differences were evident in relation to gender or to presence of diabetes. Changes in body fat mass per month correlated negatively with bas eline serum albumin concentration (r = -0.449, P < 0.0001) and baseline bod y fat mass (r = -0.423, P < 0.001). These factors independently influenced the change according to multiple regression analysis (R-2 = 0.323, P < 0.00 01). In conclusion, body fat mass increases significantly in the first year of maintenance hemodialysis, especially in patients with poor nutritional status. More general, dual x-ray absorptiometry assessment of body fat mass was found to be useful for evaluating the nutritional status of hemodialys is patients.