Cytotoxicity of Ganoderma lucidum triterpenes

Citation
Ts. Wu et al., Cytotoxicity of Ganoderma lucidum triterpenes, J NAT PROD, 64(8), 2001, pp. 1121-1122
Citations number
8
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
8
Year of publication
2001
Pages
1121 - 1122
Database
ISI
SICI code
0163-3864(200108)64:8<1121:COGLT>2.0.ZU;2-I
Abstract
Two new triterpenoids, lucidenic acid N(1) and methyl lucidenate F (2), tog ether with four known compounds, lucidenic acid A, lucidenolactone, luciden ic acid C, and ganoderic acid E, were isolated from the dried fruiting bodi es of Ganoderma lucidum. Their struct-es were elucidated by spectral and ch emical transformation studies. Among them, lucidenic acid N (1), lucidenic acid A, and ganoderic acid E showed significant cytotoxic activity against Hep G2, Hep G2,2,15, and P-388 tumor cells.