Thymol derivatives from Eupatorium fortunei

Citation
M. Tori et al., Thymol derivatives from Eupatorium fortunei, J NAT PROD, 64(8), 2001, pp. 1048-1051
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
8
Year of publication
2001
Pages
1048 - 1051
Database
ISI
SICI code
0163-3864(200108)64:8<1048:TDFEF>2.0.ZU;2-A
Abstract
Sixteen new thymol derivatives have been isolated from Eupatorium fortunei and their structures determined based on spectroscopic data. They were clas sified into three groups (i-iii) depending on the oxidation levels: (i) one oxygen function at the 9-position, (ii) two oxygen functions at the 8- and 9-positions, and (iii) three oxygen functions at the 8-, 9-, and 10-positi ons. The hydroxyl groups are acylated with tigloyl, angeloyl, acetyl, isobu tyryl, 3-methyl-2-butenoyl, or 2-methylbutyryl moieties. The compounds havi ng chiral centers showed no specific rotation and exist as racemic mixtures .