Synthesis and NMR spectroscopic studies of optically active derivatives ofgamma-aminobutenoic acids and 2-amino-pyrrolin-4-ones

Citation
M. Petroliagi et O. Igglessi-markopoulou, Synthesis and NMR spectroscopic studies of optically active derivatives ofgamma-aminobutenoic acids and 2-amino-pyrrolin-4-ones, J HETERO CH, 38(4), 2001, pp. 917-922
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
JOURNAL OF HETEROCYCLIC CHEMISTRY
ISSN journal
0022-152X → ACNP
Volume
38
Issue
4
Year of publication
2001
Pages
917 - 922
Database
ISI
SICI code
0022-152X(200107/08)38:4<917:SANSSO>2.0.ZU;2-7
Abstract
An efficient method for the preparation of optically active derivatives of gamma -amino-butenoic acids and their cyclic derivatives, 2-amino-pyrrolin- 4-ones, from alpha -amino acids is described. Partial racemization accompan ies the formation of initial unsaturated gamma -amino- beta -hydroxy esters 5-8, as determined by chiral HPLC.