Evaluation of near patient testing for Chlamydia trachomatis in a pregnancy termination service

Citation
J. Hopwood et al., Evaluation of near patient testing for Chlamydia trachomatis in a pregnancy termination service, J FAM PLAN, 27(3), 2001, pp. 127
Citations number
7
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Public Health & Health Care Science
Journal title
JOURNAL OF FAMILY PLANNING AND REPRODUCTIVE HEALTH CARE
ISSN journal
1471-1893 → ACNP
Volume
27
Issue
3
Year of publication
2001
Database
ISI
SICI code
1471-1893(200107)27:3<127:EONPTF>2.0.ZU;2-K
Abstract
Aim. To identify and evaluate advantages and disadvantages of a near patien t test (NPT) for Chlamydia trachomatis, using Clearview Chlamydia MF (Unipa th Ltd) in a British Pregnancy Advisory Service (BPAS) clinic. Method. The improved Clearview Chlamydia MF test was used to test endocervical swabs fr om 400 women attending BPAS clinic for termination of pregnancy. The result s were compared with Ligase Chain Reaction (LCR), using Polymerase Chain Re action (PCR) as the arbiter. Results. Twenty-seven women tested positive by Clearview Chlamydia MF (24 confirmed by LCR) and 32 by LCR. Comment. NPT h as potential advantages in specific situations where a quick result is requ ired for optimal management of those testing positive. However, the current technology, available for detection of Chlamydial infection results in tim e constraints, which limited its benefits in this study, where there was a high throughput of clients. A significant number of cases were missed by Clearview Chlamydia MF, though the sensitivity found is within the ranges reported for various enzyme imm unoassays (EIA) currently the most commonly used testing method. The study, confirmed the high positivity in those attending for termination , especially in under 25-year-olds.