Genes for neurotrophic factors and their receptors: structure and regulation

Authors
Citation
M. Metsis, Genes for neurotrophic factors and their receptors: structure and regulation, CELL MOL L, 58(8), 2001, pp. 1014-1020
Citations number
51
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
CELLULAR AND MOLECULAR LIFE SCIENCES
ISSN journal
1420-682X → ACNP
Volume
58
Issue
8
Year of publication
2001
Pages
1014 - 1020
Database
ISI
SICI code
1420-682X(200107)58:8<1014:GFNFAT>2.0.ZU;2-N
Abstract
Neurotrophins and their receptors have attracted much interest during the l ast two decades. Although the mode of action of molecules of the neurotroph in system has been studied extensively, information on molecular mechanisms governing their expression is mosaic and incomplete. This review attempts to summarize the data available on gene structure and transcriptional regul ation of neurotrophins and their receptors, and outlines perspectives for t he future in this field.