Respiratory tract infections by Mycoplasma pneumoniae in children: a review of diagnostic and therapeutic measures

Citation
A. Ferwerda et al., Respiratory tract infections by Mycoplasma pneumoniae in children: a review of diagnostic and therapeutic measures, EUR J PED, 160(8), 2001, pp. 483-491
Citations number
132
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
EUROPEAN JOURNAL OF PEDIATRICS
ISSN journal
0340-6199 → ACNP
Volume
160
Issue
8
Year of publication
2001
Pages
483 - 491
Database
ISI
SICI code
0340-6199(200108)160:8<483:RTIBMP>2.0.ZU;2-5
Abstract
This review discusses the current knowledge on laboratory tests and treatme nt of respiratory tract infections caused by Mycoplasma pneumoniae (MP) in children. MP infection is endemic in most areas of the world. The highest i ncidence is seen in children aged between 3 and 14 years. Most infections a re mild and non-pneumonic. Parapneumonic complications of MP pneumonia are rare. Complications are described affecting the skin, central nervous syste m, kidneys, heart, muscles and the eyes. To diagnose an acute MP infection in children, a combination of PCR and IgM serology is sensitive and conveni ent. In both tests it is possible to obtain a result in I to 2 days. As a c onsequence, adequate antibiotic treatment can be prescribed to the child. M acrolides are the first choice in treatment of MP infection in children. Conclusion The most sensitive and rapid test to diagnose a Mycoplasma pneum oniae infection in children is a combination of nasopharyngeal polymerase c hain reaction and IgM enzyme immunoassay. The treatment of choice in childr en is a macrolide.