Fluorine-18 fluorodeoxyglucose (F-18 FDG) has been used to evaluate early-s
tage larynx cancer and metastases of thyroid cancer. However, elevated F-18
FDG uptake in laryngeal muscles may lead to misinterpretation. In this rep
ort, three patients with thyroid cancer are described who had thyroid surge
ry 2 months to 1 year before F-18 FDG positron emission tomographic imaging
. Various degrees of moderate to intense uptake were observed in their lary
ngeal regions. In one patient, this was caused by laryngeal muscle uptake.
To determine the origin of the increased muscle uptake in the other two pat
ients, the authors analyzed the position and shape of the foci of high upta
ke in light of the patients' clinical histories and other imaging results.