Scintigraphic evaluation of pamidronate and corticosteroid therapy in a patient with progressive diaphyseal dysplasia (Camurati-Engelmann disease)

Citation
T. Inaoka et al., Scintigraphic evaluation of pamidronate and corticosteroid therapy in a patient with progressive diaphyseal dysplasia (Camurati-Engelmann disease), CLIN NUCL M, 26(8), 2001, pp. 680-682
Citations number
7
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
CLINICAL NUCLEAR MEDICINE
ISSN journal
0363-9762 → ACNP
Volume
26
Issue
8
Year of publication
2001
Pages
680 - 682
Database
ISI
SICI code
0363-9762(200108)26:8<680:SEOPAC>2.0.ZU;2-Q
Abstract
A 27-year-old woman with progressive diaphyseal dysplasia (Camurati-Engelma nn disease) received pamidronate and corticosteroid therapy for bone pain. During therapy, disease activity was assessed serially using bone scintigra phy with Tc-99m HMDP. With pamidronate administration, the bone pain became worse and diaphyseal uptake of Tc-99m HMDP increased whereas corticosteroi d administration improved the bone pain and reduced the diaphyseal uptake. In this case, pamidronate and corticosteroid produced different effects. Bo ne scintigraphy allowed an objective assessment of the response to these tr eatments, accurately reflecting clinical symptoms.