Signal transduction via the growth hormone receptor

Citation
T. Zhu et al., Signal transduction via the growth hormone receptor, CELL SIGNAL, 13(9), 2001, pp. 599-616
Citations number
262
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
CELLULAR SIGNALLING
ISSN journal
0898-6568 → ACNP
Volume
13
Issue
9
Year of publication
2001
Pages
599 - 616
Database
ISI
SICI code
0898-6568(200109)13:9<599:STVTGH>2.0.ZU;2-F
Abstract
Rapid progress has been made recently in the definition of growth hormone ( GH) receptor signal transduction pathways. It is now apparent that many cyt okines, including GH, share identical or similar signalling components to e xert their cellular effects. This review provides a brief discourse on the signal transduction pathways, which have been demonstrated to be utilized b y GH. The identification of such pathways provides a basis for understandin g the pleiotropic actions of GH. The mechanisms by which the specific cellu lar effects of GH are achieved remain to be elucidated. (C) 2001 Elsevier S cience Inc. All rights reserved.