Timing and localization of movement-related spectral changes in the human peri-Rolandic cortex: Intracranial recordings

Citation
J. Klopp et al., Timing and localization of movement-related spectral changes in the human peri-Rolandic cortex: Intracranial recordings, NEUROIMAGE, 14(2), 2001, pp. 391-405
Citations number
47
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences & Behavoir
Journal title
NEUROIMAGE
ISSN journal
1053-8119 → ACNP
Volume
14
Issue
2
Year of publication
2001
Pages
391 - 405
Database
ISI
SICI code
1053-8119(200108)14:2<391:TALOMS>2.0.ZU;2-J
Abstract
Event-related spectral power (ERSP) was measured from intracranial EEG and used to characterize the time-course and localization of the Rolandic mu rh ythms in 12 patients during the delayed recognition of words or faces (DR) and the discrimination of simple lateralized visual targets (LVD). On each trial, the subject decided whether to make manual response (Go) or not (NoG o). ERSP increased on both Go and NoGo trials in peri-Rolandic regions of a ll subjects with a peak latency of similar to 330-ms poststimulus and durat ion of 260 ms during the DR task. The peak of this ERSP increase preceded m ovement by similar to 300 ms. All subjects produced a subsequent movement s pecific ERSP decrease of peri-Rolandic mu rhythms (starting similar to 90 m s before the average reaction time) with an peak latency of similar to 800 ms and duration of similar to 520 ms. The LVD task produced bilateral movem ent-selective readiness potentials and reproduced the movement-specific lat e ERSP decreases seen in the DR task (strongest from 7-24 Hz). Furthermore, the LVD task demonstrated that the late movement-related ERSP decrease is larger for the contralateral hand. However, the LVD task did not consistent ly reproduce the early ERSP increase seen in the DR task. Movement-related ERSP decreases were widespread, occurring in pre- and post-Rolandic as well as primary-motor, supplemental motor, and cingulate cortical regions. Othe r cortical areas including frontal, temporal, and occipital regions did not show movement-related ERSP changes. Peri-Rolandic ERSP decreases in mu rhy thms correlate with the generation of a motor command. The early increases in mu. may reflect a transient state of motor inhibition just prior to moto r execution. (C) 2001 Academic Press.