Identification of a regulatory allele of teashirt (tsh) in Drosophila melanogaster that affects wing hinge development. An adult-specific tsh enhancer in Drosophila

Citation
Kh. Soanes et al., Identification of a regulatory allele of teashirt (tsh) in Drosophila melanogaster that affects wing hinge development. An adult-specific tsh enhancer in Drosophila, MECH DEVEL, 105(1-2), 2001, pp. 145-151
Citations number
22
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cell & Developmental Biology
Journal title
MECHANISMS OF DEVELOPMENT
ISSN journal
0925-4773 → ACNP
Volume
105
Issue
1-2
Year of publication
2001
Pages
145 - 151
Database
ISI
SICI code
0925-4773(200107)105:1-2<145:IOARAO>2.0.ZU;2-1
Abstract
A cis-acting regulatory element defined herein is required to drive teashir t (tsh) expression in the regions of the developing adult that give rise to proximal wing and haltere tissues. Loss of this expression results in the fusion of the proximal structures of the wing and halteres to the thoracic cuticle. This represents the first description of a viable adult-specific r egulatory allele of tsh with a visible phenotype, and it enlarges our under standing of the expression of tsh and its function during the development o f the adult. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.