New steroid glycosides from the starfish Asterias rathbuni

Citation
Nv. Ivanchina et al., New steroid glycosides from the starfish Asterias rathbuni, J NAT PROD, 64(7), 2001, pp. 945-947
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
7
Year of publication
2001
Pages
945 - 947
Database
ISI
SICI code
0163-3864(200107)64:7<945:NSGFTS>2.0.ZU;2-G
Abstract
Two novel steroidal 24-O-xylosides, designated as rathbuniosides R-1 (1) an d R-2 (2), and the known amurensoside A (3) and 3-O-sulfomarthasterone (4) have been isolated from the starfish Asterias rathbuni. The structures of a ll the compounds were determined from their spectroscopic data, including o ne- and two-dimensional NMR methods. The compounds I and 4 inhibit the cell division of fertilized sea urchin eggs at doses of 7.0 x 10(-5) and 2.9 x 10(-5) M, respectively.