Prunioside A: A new terpene glycoside from Spiraea prunifolia

Citation
H. Oh et al., Prunioside A: A new terpene glycoside from Spiraea prunifolia, J NAT PROD, 64(7), 2001, pp. 942-944
Citations number
13
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
7
Year of publication
2001
Pages
942 - 944
Database
ISI
SICI code
0163-3864(200107)64:7<942:PAANTG>2.0.ZU;2-F
Abstract
Prunioside A (1) has been isolated from an EtOAc-soluble extract of Spiraea prunifolia var. simpliciflora by a combination of chromatographic techniqu es. The structure was determined primarily by extensive NMR experiments. Co mpound 1 is a unique terpene glycoside. Its acetylated derivative (1a) inhi bited nitric oxide production in murine macrophage-like RAW 264.7 cells in a dose-dependent manner.