Monoterpene glycosides and triterpene acids from Eriobotrya deflexa

Lee, TH Lee, SS Kuo, YC Chou, CH

Th. Lee et al., Monoterpene glycosides and triterpene acids from Eriobotrya deflexa, J NAT PROD, 64(7), 2001, pp. 865-869

23

INGLESE

Article

Agricultural Chemistry","Pharmacology & Toxicology

JOURNAL OF NATURAL PRODUCTS

0163-3864 → ACNP

64

7

2001

865 - 869

ISI

0163-3864(200107)64:7<865:MGATAF>2.0.ZU;2-X

A phytochemical study on a methanolic extract of leaves of Eriobotrya defle xa led to the isolation and characterization of nine terpenoid compounds. F our of these are new chemical entities, including two monoterpene glycoside s, (3S)-O-alpha -L-rhamnopyranosyl-(1-->3)-[4-O-(E)-coumaroyl]-alpha -L-rha mnopyranosyl(1-->6)-beta -D-glucopyranosyl-linalool (1) and (3S)-O-alpha -L -rhamnopyranosyl-(1-->3)-[4-O-(Z)-coumaroyl]-alpha -L-rhamnopyranosyl-(1--> 6)-beta -D-glucopyranosyl-linalool (2), and two triterpene acids, 1 beta ,2 alpha ,19 alpha -trihydroxy-3-oxo-12-ursen-28-oic acid (3) and 2 alpha ,3 alpha ,19 alpha -trihydroxy-12-oleanen-28-oic acid (4). Their structures we re elucidated on the basis of spectroscopic analysis. The activities of the se isolates in an in vitro antiproliferation test were also determined.