Expression of Xenopus L-arginine : glycine amidinotransferase (XAT) duringearly embryonic development

Citation
H. Zhao et al., Expression of Xenopus L-arginine : glycine amidinotransferase (XAT) duringearly embryonic development, DEV GENES E, 211(7), 2001, pp. 358-360
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cell & Developmental Biology
Journal title
DEVELOPMENT GENES AND EVOLUTION
ISSN journal
0949-944X → ACNP
Volume
211
Issue
7
Year of publication
2001
Pages
358 - 360
Database
ISI
SICI code
0949-944X(200107)211:7<358:EOXL:G>2.0.ZU;2-1
Abstract
We have isolated a full-length cDNA encoding Xenopus L-arginine:glycine ami dinotransferase (XAT), which shares a highly conserved sequence with human, chick and rat amidinotransferase. Although there are some studies about it s structure and function in energy metabolism of adult tissues in some othe r species, little is known about its roles during early embryonic developme nt. Characterization of embryonic expression indicates that XAT is differen tially expressed around the yolk plug including the dorsal blastopore area at early gastrula stages and is extensively expressed in the midline of the neural plate of early neurula stages: Sections reveal that its transcripts are located in the notochord. In the tailbud stage signals are found both in the notochord and trunk area, whereas only faint signals can be found in the cephalic part.