Exposures and cancer incidence near oil fields in the Amazon basin of Ecuador

Citation
M. San Sebastian et al., Exposures and cancer incidence near oil fields in the Amazon basin of Ecuador, OCC ENVIR M, 58(8), 2001, pp. 517-522
Citations number
49
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Envirnomentale Medicine & Public Health","Pharmacology & Toxicology
Journal title
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
ISSN journal
1351-0711 → ACNP
Volume
58
Issue
8
Year of publication
2001
Pages
517 - 522
Database
ISI
SICI code
1351-0711(200108)58:8<517:EACINO>2.0.ZU;2-F
Abstract
Objectives - To examine environmental exposure and incidence and mortality of cancer in the village of San Carlos surrounded by oil fields in the Amaz on basin of Ecuador. Methods - Water samples of the local streams were analyzed for total petrol eum hydrocarbons (TPHs). A preliminary list of potential cancer cases from 1989 to 1998 was prepared. Cases were compared with expected numbers of can cer morbidity and mortality registrations from a Quite reference population . Results - Water analysis showed severe exposure to TPHs by the residents. T en patients with cancer were diagnosed while resident in the village of San Carlos. An overall excess for all types of cancer was found in the male po pulation (8 observed v 3.5 expected) with a risk 2.26 times higher than exp ected (95% confidence interval (95% CI) 0.97 to 4.46). There was an overall excess of deaths for all types of cancer (6 v 1.6 expected) among the male population 3.6 times higher than the reference population (95% CI 1.31 to 7.81). Conclusions-The observed excess of cancer might be associated with the poll ution of the environment by toxic contaminants coming from the oil producti on.