Lack of an association between cystatin C gene polymorphisms in Japanese patients with Alzheimer's disease

Citation
H. Maruyama et al., Lack of an association between cystatin C gene polymorphisms in Japanese patients with Alzheimer's disease, NEUROLOGY, 57(2), 2001, pp. 337-339
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
0028-3878 → ACNP
Volume
57
Issue
2
Year of publication
2001
Pages
337 - 339
Database
ISI
SICI code
0028-3878(20010724)57:2<337:LOAABC>2.0.ZU;2-Q
Abstract
Associations between polymorphisms of the cystatin C gene (CST3) at 5' flan king region and exon 1 in Caucasian patients with late onset AD and exon 1 in a US study of late onset AD have been reported. Clinically diagnosed Jap anese patients with AD and Japanese normal control subjects were assessed f or the presence of polymorphisms of CST3. The authors could not confirm the previously reported association between CST3 polymorphisms and AD in Japan . Age had no effect on the CST3 genotype.