Mechanisms by which metals promote events connected to neurodegenerative diseases

Citation
A. Campbell et al., Mechanisms by which metals promote events connected to neurodegenerative diseases, BRAIN RES B, 55(2), 2001, pp. 125-132
Citations number
113
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences & Behavoir
Journal title
BRAIN RESEARCH BULLETIN
ISSN journal
0361-9230 → ACNP
Volume
55
Issue
2
Year of publication
2001
Pages
125 - 132
Database
ISI
SICI code
0361-9230(20010515)55:2<125:MBWMPE>2.0.ZU;2-F
Abstract
Although the exact causative phenomenon responsible for the onset and progr ession of neurodegenerative disorders is at present unresolved, there are s ome clues as to the mechanisms underlying these chronic diseases. This revi ew addresses mechanisms by which endogenous or environmental factors, throu gh interaction with redox active metals, may initiate a common cascade of e vents terminating in neurodegeneration. (C) 2001 Elsevier Science Inc.