Ion interaction chromatography of neutral molecules. use of a potential approximation to obtain a simplified retention equation

Citation
T. Cecchi et al., Ion interaction chromatography of neutral molecules. use of a potential approximation to obtain a simplified retention equation, J LIQ CHR R, 24(3), 2001, pp. 291-302
Citations number
27
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
ISSN journal
1082-6076 → ACNP
Volume
24
Issue
3
Year of publication
2001
Pages
291 - 302
Database
ISI
SICI code
1082-6076(2001)24:3<291:IICONM>2.0.ZU;2-8
Abstract
The chromatographic behavior of neutral molecules in Ion Interaction Chroma tography (IIC) was theoretically investigated. The use of a potential appro ximation to obtain a simplified retention equation was successfully tested. The most reliable experimental literature results, concerning the retentio n behavior of neutral molecules in IIC, were successfully fitted by the ret ention equation. The wide variability among them was elucidated on the basis of the develope d retention equation. A new separation strategy, to improve the selectivity of the chromatographic method, for difficult to separate mixtures of neutr al eluates was proposed.