Selected steroids have been separated by reversed phase thin layer chromato
graphy and reversed phase high performance liquid chromatography. The chrom
atographic data (R-M and log k'), and partition coefficient (log P) values
of the compounds have been correlated with the numerical values of topologi
cal indices. The most accurate predictions of the R-M, logk', and log P val
ues of the selected steroids were achieved by using monoparametric equation
s employing the topological indices B-o.