Chromatographic data - Topological index dependence for selected steroids

Authors
Citation
A. Pyka, Chromatographic data - Topological index dependence for selected steroids, J LIQ CHR R, 24(4), 2001, pp. 453-460
Citations number
31
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES
ISSN journal
1082-6076 → ACNP
Volume
24
Issue
4
Year of publication
2001
Pages
453 - 460
Database
ISI
SICI code
1082-6076(2001)24:4<453:CD-TID>2.0.ZU;2-T
Abstract
Selected steroids have been separated by reversed phase thin layer chromato graphy and reversed phase high performance liquid chromatography. The chrom atographic data (R-M and log k'), and partition coefficient (log P) values of the compounds have been correlated with the numerical values of topologi cal indices. The most accurate predictions of the R-M, logk', and log P val ues of the selected steroids were achieved by using monoparametric equation s employing the topological indices B-o.