MUTAGENICITY, CARCINOGENICITY AND TERATOGENICITY OF THALLIUM COMPOUNDS

Citation
A. Leonard et Gb. Gerber, MUTAGENICITY, CARCINOGENICITY AND TERATOGENICITY OF THALLIUM COMPOUNDS, Mutation research-reviews in mutation research, 387(1), 1997, pp. 47-53
Citations number
56
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Genetics & Heredity",Toxicology
Volume
387
Issue
1
Year of publication
1997
Pages
47 - 53
Database
ISI
SICI code
Abstract
The paper reviews the information available concerning the mutagenic, carcinogenic and teratogenic effects of thallium. Data on mutagenic an d carcinogenic risks of thallium and its compounds are extremely scant y but what is available does not indicate that thallium could be mutag enic or carcinogenic. At any rate, such risks, if they exist, would be submerged by the general high toxicity of thallium. On the other hand , thallium has some teratogenic properties, especially on cartilage an d bone formation, although this seems to be more prominent in chicks t han in mammals. Nevertheless, pregnant women should not be exposed to doses of thallium which might produce toxic symptoms; exposure to lowe r doses such as might occur near thallium-emitting plants is probably not embryotoxic.