Background, Modality of living donor liver transplantation (LDLT) has been
expanded to adult cases. However, the safety of right lobectomy from living
donors has not yet been proven.
Methods. A total of 62 cases of LDLT, using the right lobe, were reviewed.
Study 1: Discrepancy between estimated graft volume and actual graft weight
was evaluated. Study 2: Postoperative liver functions were analyzed in rel
ation to residual liver volume (RLV) or age. Residual liver volume of donor
s was defined using two indices, (RLV = estimated whole liver volume estima
ted graft volume and %RLV = RLV/estimated whole liver volume x 100). Donors
were divided into two groups on the basis of either %RLV (< 40%; 40%less t
han or equal to) or age (< 50 years old; 50 years old less than or equal to
). Study 3: Right lobe donors were compared with left lobe donors (35 cases
) in terms of their postoperative liver functions.
Results. Study 1: The relationship between estimated graft volume and actua
l graft weight was linear (y= 159.136+ 0.735x, R-2=0.571, P <0.001). Study
2: %RLV ranged from 23.5% to 55.8% (mean +/- SD: 43.2 +/-6.0). Fifteen case
s showed %RLV less than 40%, Postoperative bilirubin clearance was delayed
in that group (%RLV < 40%). Serum total bilirubin values on postoperative d
ay 7 in the older group (age greater than or equal to 50) were significantl
y higher than those in the younger group (age < 50), Study 3: Postoperative
liver functions of right lobe donors were significantly higher than those
of left-lobe donors, Eleven donors (17.7%) had surgical complications, all
of which were cured with proper treatment.
Conclusions. Right lobectomy from living donors is a safe procedure with ac
ceptable morbidity, but some care should be taken early after the operation
for donors with small residual liver and aged donors.