Background: EUS can provide detailed imaging of pancreatic malignancies and
direct fine needle aspiration (FNA) of pancreatic masses,The ability of EU
S to detect and stage malignancy in cystic and intraductal lesions has not
been investigated. Our aim was to determine the sensitivity and specificity
of EUS imaging and FNA in detecting and staging of malignancy in solid, cy
stic, and intraductal lesions of the pancreas.
Methods: The records of 96 patients (46 solid, 26 cystic, 24 intraductal le
sions) who underwent EUS followed by surgical exploration over a 3-year per
iod were reviewed, The accuracy of EUS for detecting and staging malignancy
was calculated based on the results of surgery and histology.
Results: EUS-guided FNA provided evidence of malignancy in solid, cystic, a
nd ductal lesions with sensitivities of 59.5%, 50%, and 60%, respectively.
The accuracy of staging by EUS was significantly less for intraductal lesio
ns (47%), compared with cystic (100%) and solid lesions (85%) (p < 0.05).
Conclusions: EUS can be used to detect malignancy in cystic and intraductal
tumors of the pancreas.