Detection and tumor staging of malignancy in cystic, intraductal, and solid tumors of the pancreas by EUS

Citation
Sl. Brandwein et al., Detection and tumor staging of malignancy in cystic, intraductal, and solid tumors of the pancreas by EUS, GASTROIN EN, 53(7), 2001, pp. 722-727
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Gastroenerology and Hepatology
Journal title
GASTROINTESTINAL ENDOSCOPY
ISSN journal
0016-5107 → ACNP
Volume
53
Issue
7
Year of publication
2001
Pages
722 - 727
Database
ISI
SICI code
0016-5107(200106)53:7<722:DATSOM>2.0.ZU;2-A
Abstract
Background: EUS can provide detailed imaging of pancreatic malignancies and direct fine needle aspiration (FNA) of pancreatic masses,The ability of EU S to detect and stage malignancy in cystic and intraductal lesions has not been investigated. Our aim was to determine the sensitivity and specificity of EUS imaging and FNA in detecting and staging of malignancy in solid, cy stic, and intraductal lesions of the pancreas. Methods: The records of 96 patients (46 solid, 26 cystic, 24 intraductal le sions) who underwent EUS followed by surgical exploration over a 3-year per iod were reviewed, The accuracy of EUS for detecting and staging malignancy was calculated based on the results of surgery and histology. Results: EUS-guided FNA provided evidence of malignancy in solid, cystic, a nd ductal lesions with sensitivities of 59.5%, 50%, and 60%, respectively. The accuracy of staging by EUS was significantly less for intraductal lesio ns (47%), compared with cystic (100%) and solid lesions (85%) (p < 0.05). Conclusions: EUS can be used to detect malignancy in cystic and intraductal tumors of the pancreas.