Spontaneous macrocyclization via recombination of a Schiff-base linkage

Citation
H. Houjou et al., Spontaneous macrocyclization via recombination of a Schiff-base linkage, TETRAHEDR L, 42(23), 2001, pp. 3861-3863
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
0040-4039 → ACNP
Volume
42
Issue
23
Year of publication
2001
Pages
3861 - 3863
Database
ISI
SICI code
0040-4039(20010604)42:23<3861:SMVROA>2.0.ZU;2-6
Abstract
A macrocyclic compound that has two salenH(2) moieties was synthesised via recombination of an acyclic Schiff base in quite high yield, and was charac terized by X-ray crystallography. The recombination occurred in a slow diff usion system of chloroform-methanol, where the starting material may sponta neously form a molecular assembly suitable for the subsequent reaction. Thi s assumption was supported by the crystal structure of an analogue of the a cyclic Schiff base. (C) 2001 Elsevier Science Ltd. All rights reserved.