Reaction of 3-iodochromone with nucleophiles 3. Formation of 2-aminomethylene-3(2H)-benzofuranones by the reaction with secondary amines

Citation
Y. Sugita et al., Reaction of 3-iodochromone with nucleophiles 3. Formation of 2-aminomethylene-3(2H)-benzofuranones by the reaction with secondary amines, HETEROCYCLE, 55(5), 2001, pp. 881-888
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
0385-5414 → ACNP
Volume
55
Issue
5
Year of publication
2001
Pages
881 - 888
Database
ISI
SICI code
0385-5414(20010501)55:5<881:RO3WN3>2.0.ZU;2-T
Abstract
3-Iodochromone (4a) easily reacted with secondary amines in the presence of potassium carbonate to give 2-aminomethylene-3(2H)-benzofuranones in good yields. Under similar conditions without potassium carbonate, 4a was reacte d with piperidine to give the enamino ketone (5) as the major product.