Comparison of quadrupole, time-of-flight, and Fourier transform mass analyzers for LC-MS applications

Citation
Bk. Choi et al., Comparison of quadrupole, time-of-flight, and Fourier transform mass analyzers for LC-MS applications, LC GC N AM, 19(5), 2001, pp. 514
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
LC GC NORTH AMERICA
ISSN journal
1527-5949 → ACNP
Volume
19
Issue
5
Year of publication
2001
Database
ISI
SICI code
1527-5949(200105)19:5<514:COQTAF>2.0.ZU;2-D
Abstract
The authors investigated the analytical capabilities of quadrupole, time-of -flight, and Fourier transform mass analyzers for liquid chromatography ele ctrospray mass spectrometry (LC-MS) applications. They studied instrument p arameters - such as sensitivity, mass range, and mass resolution - and issu es related to sample preparation and separation for the characterization of low molecular weight compounds in complex environmental matrices. In this article, the authors discuss the effect of sample preparation on the perfor mance of LC-MS analytical methods.