Standardization of laboratory data and establishment of reference intervals in the fukuoka prefecture: A Japanese perspective

Kinoshita, S Toyofuku, M Iida, H Wakiyama, M Kurihara, M Nakahara, M Nakata, M Nakashima, K Seo, S Hosaka, N Yano, J Mizumoto, T Ishihara, H Ikeda, K Tsuchihashi, M Kawashima, H Imoto, Y Imamura, K Urabe, Y Shinohara, K Ooishi, K Abe, T Jinnouchi, J Hyoudou, K Kondo, S Kobayashi, T Ono, J Hamasaki, N

S. Kinoshita et al., Standardization of laboratory data and establishment of reference intervals in the fukuoka prefecture: A Japanese perspective, CLIN CH L M, 39(3), 2001, pp. 256-262

16

INGLESE

Article

Medical Research Diagnosis & Treatment

CLINICAL CHEMISTRY AND LABORATORY MEDICINE

1434-6621 → ACNP

39

3

2001

256 - 262

ISI

1434-6621(200103)39:3<256:SOLDAE>2.0.ZU;2-W

Standardization of 22 clinical chemistry analytes and five serum protein co nstituents has been performed in the Fukuoka Prefecture, which has a popula tion of approximately five million. The standardization project was establi shed to determine reference intervals for these analytes by educating physi cians, medical technologists and staff of medical institutions, and by dail y or monthly monitoring the use of common control samples through e-mail. S tandardization extended to 97% of the institutions in the prefecture. Resul ts for 14 of the 22 clinical chemistry analytes have become highly reliable and differences between institutions decreased. Standardization of other a nalytes is now in progress. Regional collaboration based on international g uidelines led to a significant improvement in interlaboratory comparability . Areas where further improvements are needed have been identified.