Highly efficient Heck reactions of aryl bromides with n-butyl acrylate mediated by a palladium/phosphine-imidazolium salt system

Citation
Cl. Yang et al., Highly efficient Heck reactions of aryl bromides with n-butyl acrylate mediated by a palladium/phosphine-imidazolium salt system, ORG LETT, 3(10), 2001, pp. 1511-1514
Citations number
39
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
1523-7060 → ACNP
Volume
3
Issue
10
Year of publication
2001
Pages
1511 - 1514
Database
ISI
SICI code
1523-7060(20010517)3:10<1511:HEHROA>2.0.ZU;2-8
Abstract
A new phosphine-imidazolium salt, L.HBr (1 . HBR = (1-ethylenediphenylphosp hino-3-(mesityl))imidazol-2-ylidene), has been prepared, A combination of 0 .5 mol % of Pd(dba)(2) and 0.5 mol % of L . HBr in the presence of 2 equiv of Cs2CO3 as base has proven to be highly efficient in the Heck coupling re actions of aryl bromides (from electron deficient to electron-rich aryl bro mides) with n-butyl acrylate.