Growth characteristics of ameloblastoma involving the inferior alveolar nerve: A clinical and histopathologic study

Citation
N. Nakamura et al., Growth characteristics of ameloblastoma involving the inferior alveolar nerve: A clinical and histopathologic study, ORAL SURG O, 91(5), 2001, pp. 557-562
Citations number
16
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Dentistry/Oral Surgery & Medicine
Journal title
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS
ISSN journal
1079-2104 → ACNP
Volume
91
Issue
5
Year of publication
2001
Pages
557 - 562
Database
ISI
SICI code
1079-2104(200105)91:5<557:GCOAIT>2.0.ZU;2-O
Abstract
Objective. Growth characteristics of amelohlastomas involving the inferior alveolar nerve were examined to determine the most appropriate surgical man agement of the nerve at the time of the surgical procedure. Study design, Clinical and histopathologic examinations were performed on 2 2 resected mandibles in which the inferior alveolar nerve was lying adjacen t to, or contained within, the tumor. Results. Patterns of tumor involvement of the nerve bundle were evaluated w ith respect to the presence of bone (11 patients) or connective tissue wall (7 patients) between the tumor and the nerve bundle, and tumor infiltratio n of perineural connective tissue (4 patients). Neither invasion into the n erve sheath nor invasion into the nerve itself by the ameloblastoma was det ected. Tumor infiltration of the tissue surrounding the nerve was identifie d for the multicystic and solid types but not for the unicystic type. Prese nce of bone or connective tissue wall between the tumor and the nerve bundl e was dominant in the unicystic and plexiform ameloblastomas, whereas tumor infiltration of the perineural tissue was frequently observed in ameloblas tomas with the follicular pattern. Conclusion. The preservation of the inferior alveolar nerve may be possible in the management of the unicystic type of ameloblastoma. However, a more radical approach is necessary for treatment of multicystic or solid tumors, especially those exhibiting a follicular pattern.