Seasonal distribution of births in patients with Alzheimer's disease and elderly depressive patients

Citation
U. Ptok et al., Seasonal distribution of births in patients with Alzheimer's disease and elderly depressive patients, EUR PSYCHIA, 16(3), 2001, pp. 157-161
Citations number
27
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Psychiatry,"Clinical Psycology & Psychiatry
Journal title
EUROPEAN PSYCHIATRY
ISSN journal
0924-9338 → ACNP
Volume
16
Issue
3
Year of publication
2001
Pages
157 - 161
Database
ISI
SICI code
0924-9338(200104)16:3<157:SDOBIP>2.0.ZU;2-4
Abstract
Winter births have been associated with a higher risk of Alzheimer's diseas e (AD) and other psychiatric disorders, In the present investigation, this putative association was examined in a sample of gerontopsychiatric patient s. An analysis of the quarterly birth rates of 83 patients with AD, 78 elde rly depressive patients with an early onset and 74 patients with a late ons et of the depressive disorder, 48 patients with both AD and depression (co- morbid patients) and 107 healthy control subjects, revealed no particular s easonal distribution for any of the diagnostic groups. In AD and co-morbid patients, controlling for the ApoE genotype did not change this finding. Lo gistic regression analysis revealed the expected findings that increasing a ge and the presence of the ApoE4 allele were associated with a higher risk of dementia. Younger age and female gender were identified as risk factors for a depressive disorder. A winter birth (birth in the first three months of the year) was not associated with any of the diagnostic subgroups. We concluded that in our sample a seasonal distribution of births was not f ound to increase the risk for AD or geriatric depression. (C) 2001 Editions scientifiques et medicales Elsevier SAS.