Renal vascular damage in Japanese patients with systemic sclerosis

Citation
C. Nishijima et al., Renal vascular damage in Japanese patients with systemic sclerosis, RHEUMATOLOG, 40(4), 2001, pp. 406-409
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Rheumatology
Journal title
RHEUMATOLOGY
ISSN journal
1462-0324 → ACNP
Volume
40
Issue
4
Year of publication
2001
Pages
406 - 409
Database
ISI
SICI code
1462-0324(200104)40:4<406:RVDIJP>2.0.ZU;2-#
Abstract
Objective. To evaluate renal vascular damage in Japanese patients with syst emic sclerosis (SSc) by colour-flow Doppler ultrasonography. Methods. The pulsatility index (PI) was measured in renal interlobar and se gmental arteries by colour-few Doppler ultrasonography. Results. PI values Of interlobar arteries were increased in SSc patients (n = 53) with normal renal function compared with healthy persons (n = 16), s ystemic lupus erythematosus patients (n = 12) and dermatomyositis patients (n = 3). SSc patients with elevated PI levels had digital pitting scar, sho rt sublingual frenulum, contracture of phalanges, pulmonary fibrosis, decre ased per cent vital capacity. heart involvement, positivity for anti-topois omerase I antibody, and elevated C-reactive protein more frequently than th ose with normal PI levels. Conclusion. Although renal crisis is rare in Japanese SSc patients, our stu dy suggests that latent and subclinical renal damage exists in these patien ts.