Atypical adenomatous hyperplasia of the lung: correlation between high-resolution CT findings and histopathologic features

Citation
S. Kawakami et al., Atypical adenomatous hyperplasia of the lung: correlation between high-resolution CT findings and histopathologic features, EUR RADIOL, 11(5), 2001, pp. 811-814
Citations number
7
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
EUROPEAN RADIOLOGY
ISSN journal
0938-7994 → ACNP
Volume
11
Issue
5
Year of publication
2001
Pages
811 - 814
Database
ISI
SICI code
0938-7994(2001)11:5<811:AAHOTL>2.0.ZU;2-#
Abstract
We describe herein the CT features of atypical adenomatous hyperplasia (AAH ) of the lung and its histopathological characteristics. Among 17,919 indiv iduals screened for lung cancer by CT scanning, ten AAH nodules were detect ed in nine asymptomatic subjects. On high-resolution CT, the lesions measur ed from 6 x 6 mm to 15 x 17 mm and their CT number ranged from -500 to -760 HU. The AAHs appeared as round nodules with smooth and distinct borders an d showed a ground-glass opacity. Plain chest radiographs failed to identify all lesions. Histopathologically, AAH lesions showed atypical epithelial c ell proliferation along slightly thickened alveolar septa, Whereas it is of ten easy to differentiate these nodules from inflammatory and benign lung l esions, histopathological examination remains at present the only method to differentiate AAH from lung cancers.