Does multisite sampling improve patient heterogeneity in drug misuse research?

Citation
J. Dunn et al., Does multisite sampling improve patient heterogeneity in drug misuse research?, DRUG AL DEP, 63(1), 2001, pp. 79-85
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences & Behavoir
Journal title
DRUG AND ALCOHOL DEPENDENCE
ISSN journal
0376-8716 → ACNP
Volume
63
Issue
1
Year of publication
2001
Pages
79 - 85
Database
ISI
SICI code
0376-8716(20010601)63:1<79:DMSIPH>2.0.ZU;2-J
Abstract
The aim of this study was to investigate whether multisite sampling increas ed heterogeneity among a sample of cocaine users from Sao Paulo, Brazil. Si x hundred and fourteen cocaine users were interviewed at 23 fixed sites plu s an out-of-treatment sample. The sites were then regrouped into six main t ypes: university outpatient clinics, public outpatient clinics, public inpa tient units. private inpatient units, HIV services and non-treatment. Marke d differences were found between users recruited at these sites. especially in relation to age, gender, employment status, criminal history, history o f prostitution, previous drug misuse treatment. duration of cocaine use and lifetime use of intravenous cocaine. These results suggest that multisite sampling is a valid method for increasing patient heterogeneity, but whethe r it improves representativeness and thus the generalisability of drug misu se research is debatable. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.