Central nervous system involvement in pyothorax-associated lymphoma: ring enhancement on CT scan

Citation
S. Hara et al., Central nervous system involvement in pyothorax-associated lymphoma: ring enhancement on CT scan, ANN HEMATOL, 80(3), 2001, pp. 174-177
Citations number
19
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
ANNALS OF HEMATOLOGY
ISSN journal
0939-5555 → ACNP
Volume
80
Issue
3
Year of publication
2001
Pages
174 - 177
Database
ISI
SICI code
0939-5555(2001)80:3<174:CNSIIP>2.0.ZU;2-O
Abstract
A 71-year-old male was diagnosed as having pyothorax-associated lymphoma (P AL), a rare hematological malignancy associated with artificial pneumothora x for the treatment of pulmonary tuberculosis. Because of the low incidence , its clinical features have not been fully clarified. The PAL lesion in th is patient disappeared after local radiotherapy and corticosteroid treatmen t. However, 8 months after the initial diagnosis. he developed a variety of neurological disorders and low-grade fever. Neither recurrence of the prim ary pulmonary lesion nor nodal enlargement was observed. Immediate magnetic resonance imaging of the brain revealed a ring-enhanced mass, suggesting a brain abscess. However, through a stereotactic biopsy of the brain lesion, infiltration of PAL cells was identified. The brain lesion rapidly enlarge d despite intensive radiotherapy, and he finally died of lymphoma progressi on. This case demonstrates that PAL may progress as a type of extranodal ly mphoma, and that brain lesions may produce a ring-enhanced pattern on compu ted tomography.