Incidence of spontaneous closure of outlet ventricular septal defect

Citation
H. Tomita et al., Incidence of spontaneous closure of outlet ventricular septal defect, JPN CIRC J, 65(5), 2001, pp. 364-366
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
ISSN journal
0047-1828 → ACNP
Volume
65
Issue
5
Year of publication
2001
Pages
364 - 366
Database
ISI
SICI code
0047-1828(200105)65:5<364:IOSCOO>2.0.ZU;2-P
Abstract
The present study examined the Doppler echocardiograms of 742 patients with an outlet ventricular septal defect (VSD) who were seen at the National Ca rdiovascular Center from 1987 to 1999. Of these, 450 patients were followed for longer than I year; 161 of these 450 were younger than 12 months when first examined. During follow-up, Doppler echocardiographic examination was repeated at least once a year. The medical chaw of these patients were rev iewed. Doppler echocardiographic findings were analysed in patients whose d efect closed spontaneously:spontaneous closure at the, age of 1-25 years wa s identified in 17 (3.8%) of 450 patients who were followed for longer than 1 year, and 7 (4.3%) of the 161 patients who were younger than 12 months a t the first examination. All closed VSDs were originally smaller than 4 mm. Although 5 cases of 17 developed trivial deformity of the right coronary c usp, suggesting a prolapse, this did not progress. Of these 5, trivial aort ic regurgitation (AR) was detected in one patient, while another patient in the group of 17 developed trivial AR without any deformity of the right co ronary cusp. Aortic regurgitation was not progressive in either patient. An outlet VSD closes spontaneously in a small percentage of patients without developing progressive AR.