On-line analytical techniques for monitoring crystallisation processes of organic speciality chemicals

Citation
M. Baker et al., On-line analytical techniques for monitoring crystallisation processes of organic speciality chemicals, MOLEC CRYST, 356, 2001, pp. 273-287
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Physical Chemistry/Chemical Physics
Volume
356
Year of publication
2001
Pages
273 - 287
Database
ISI
SICI code
Abstract
In order to examine on-line batch crystallisation processes a new integrate d batch process engineering laboratory has been established providing facil ities for the on-line measurement and control of: reactant supersaturation via ATR-FTIR spectroscopy; crystal size via acoustic attenuation spectroscopy; particle perfection and polymorphic form via X-ray diffraction: crystallisation on-set and meta-stable zone width via UV vis spectroscopic turbidometric measurements. These facilities are complemented via assessment of reactant mixing as meas ured via laser doppler anemometry and simulated using multi-phase computati onal fluid dynamics. An overview of the planned research programme and mate rial systems to be examined are presented:.