Spontaneous neoplastic lesions in aged Sprague-Dawley rats

Citation
M. Nakazawa et al., Spontaneous neoplastic lesions in aged Sprague-Dawley rats, EXP ANIM, 50(2), 2001, pp. 99-103
Citations number
13
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Animal Sciences
Journal title
EXPERIMENTAL ANIMALS
ISSN journal
1341-1357 → ACNP
Volume
50
Issue
2
Year of publication
2001
Pages
99 - 103
Database
ISI
SICI code
1341-1357(200104)50:2<99:SNLIAS>2.0.ZU;2-H
Abstract
Neoplastic lesions were observed in untreated aged Sprague Dawley (SD) rats throughout their lifespan starting at 5 weeks. Their mean survival times w ere 89 to 105 weeks of age. The total tumor incidences were 70 to 76. 7% an d 87 to 95.8% in males and females, respectively. The common neoplasmas wer e pituitary adenoma and adrenal pheochromocytoma in both sexes, testicular Leydig cell tumor in males and mammary gland tumors, thyroidal C-cell adeno ma and uterine stromal polyp in females.