NreB from Achromobacter xylosoxidans 31A is a nickel-induced transporter conferring nickel resistance

Citation
G. Grass et al., NreB from Achromobacter xylosoxidans 31A is a nickel-induced transporter conferring nickel resistance, J BACT, 183(9), 2001, pp. 2803-2807
Citations number
28
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
0021-9193 → ACNP
Volume
183
Issue
9
Year of publication
2001
Pages
2803 - 2807
Database
ISI
SICI code
0021-9193(200105)183:9<2803:NFAX3I>2.0.ZU;2-D
Abstract
There are two distinct nickel resistance loci on plasmid pTOM9 from Achromo bacter xylosoxidans 31A, ncc and nre. Expression of the nreB gene was speci fically induced by nickel and conferred nickel resistance on both A. xyloso xidans 31A and Escherichia coli. E. coli cells expressing nreB showed reduc ed accumulation of Ni2+, suggesting that NreB mediated nickel efflux. The h istidine-rich C-terminal region of NreB mas not essential but contributed t o maximal Ni2+ resistance.