Vaccine effectiveness for influenza in the elderly in welfare nursing homes during an influenza A (H3N2) epidemic

Citation
Y. Deguchi et al., Vaccine effectiveness for influenza in the elderly in welfare nursing homes during an influenza A (H3N2) epidemic, EPIDEM INFE, 125(2), 2000, pp. 393-397
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medical Research General Topics
Journal title
EPIDEMIOLOGY AND INFECTION
ISSN journal
0950-2688 → ACNP
Volume
125
Issue
2
Year of publication
2000
Pages
393 - 397
Database
ISI
SICI code
0950-2688(200010)125:2<393:VEFIIT>2.0.ZU;2-L
Abstract
Influenza vaccine effect on the occurrence and severity of influenza virus infection in a population residing in nursing homes for the elderly was stu died as a cohort study during an influenza A (H3N2) epidemic in Japan. Of 2 2 462 individuals living in 301 welfare nursing homes, 10739 voluntarily re ceived inactivated, sub-unit trivalent influenza vaccine in a programme sup ported by the Osaka Prefectural Government. There were statistically signif icantly fewer cases of influenza, hospital admissions due to severe infecti on, and deaths due to influenza in the vaccinated cohort compared to the un vaccinated controls. No serious adverse reactions to vaccination were recor ded. Thus influenza vaccination is effective for preventing influenza disea se in persons aged 65 years and over, and should be an integral part of the care of this population residing in nursing homes.