Colchicine: An effective treatment for refractory malignant pericardial effusion

Citation
T. Ng et al., Colchicine: An effective treatment for refractory malignant pericardial effusion, ACT HAEMAT, 104(4), 2000, pp. 217-219
Citations number
12
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
ACTA HAEMATOLOGICA
ISSN journal
0001-5792 → ACNP
Volume
104
Issue
4
Year of publication
2000
Pages
217 - 219
Database
ISI
SICI code
0001-5792(2000)104:4<217:CAETFR>2.0.ZU;2-I
Abstract
We report a patient with AL amyloidosis and chemoresistant light-chain mult iple myeloma who developed a progressive malignant pericardial effusion lea ding to cardiac tamponade. Despite pericardiocentesis and surgical interven tion, the pericardial effusion failed to resolve. The administration of ora l colchicine produced symptomatic relief within 5 days, with the resolution of pericardial effusion after 14 days of treatment. As the administration of colchicine is simple and the side-effect is usually minimal, further stu dies are warranted to establish the feasibility of using colchicine to trea t malignant pericardial effusion. Copyright (C) 2001 S. Karger AG, Basel.