Analysis of calcium deposits in calcific periarthritis

Citation
Ji. Hamada et al., Analysis of calcium deposits in calcific periarthritis, J RHEUMATOL, 28(4), 2001, pp. 809-813
Citations number
29
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Rheumatology,"da verificare
Journal title
JOURNAL OF RHEUMATOLOGY
ISSN journal
0315-162X → ACNP
Volume
28
Issue
4
Year of publication
2001
Pages
809 - 813
Database
ISI
SICI code
0315-162X(200104)28:4<809:AOCDIC>2.0.ZU;2-C
Abstract
Objective. To determine if hydroxyapatite (HAP), octacalcuim phosphate (OCP ), or tricalcium phosphate (TCP) can be found in the calcium deposits in ca lcific periarthritis. Methods. Thirty-six specimens from 34 patients who had acute inflammation a cid roentgenographically recognized calcification in soft tissue were analy zed. Twenty-three patients with calcific tendinitis in the shoulder and 11 with calcific periarthritis at other sites were included. We prepared 2 kin ds of samples from each specimen: a dried sample (washed and dried calcific deposit), and a sample heated to 1000 degreesC. All were analyzed by X-ray diffraction, Raman spectroscopy, infrared absorption spectroscopy, and X-r ay fluorescence spectrometry for calcium and phosphorus molar ratio. Synthe tic HAP was used as the control in each analysis. Results. The X-ray diffraction patterns of all dried samples were similar t o those of HAP and carbonate apatite. We found no diffraction patterns of O CP or TCP. However. an OH- group at 3570cm(-1) was observed with Raman spec troscopy for samples heated to 1000 degreesC and synthetic HAP, but not for the dried samples. Infrared absorption spectroscopy also confirmed an OH- group for samples heated to 1000 degreesC and synthetic HAP, and confirmed that dried samples contained carbonate. Conclusion, Calcium deposits are composed of carbonate apatite. HAP, OCP, a nd TCP were not identified in any deposits.