Vasculitides associated with HIV infection

Authors
Citation
R. Chetty, Vasculitides associated with HIV infection, J CLIN PATH, 54(4), 2001, pp. 275-278
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
JOURNAL OF CLINICAL PATHOLOGY
ISSN journal
0021-9746 → ACNP
Volume
54
Issue
4
Year of publication
2001
Pages
275 - 278
Database
ISI
SICI code
0021-9746(200104)54:4<275:VAWHI>2.0.ZU;2-Y
Abstract
The manifestations of human immunodeficiency virus (HIV) infection are prot ean and vasculitides are one of the less common but nonetheless important c onsequences. A wide range of vasculitides can be encountered, ranging from vasculitis resulting from specific infective agents to a non-specific vascu litis. Among the infective causes, cytomegalovirus and tuberculosis are pro bably the most common. A polyarteritis nodosa-like vasculitis with importan t differences to classic polyarteritis nodosa is also described, Hypersensi tivity vasculitis resulting in several patterns of vasculitis and angiocent ric immunoproliferative vasculitis are well recognised. As part of the immu nocompromise caused by HIV, a granulomatous inflammation involving small ar teries and veins of the brain surface and leptomeninges, termed a primary a ngiitis of the central nervous system, is a rare vasculitis associated with high mortality, A recently described large vessel (aorta, femorals, caroti ds) vasculopathy resulting in either multiple aneurysm formation or occlusi ve disease is seen in young adults, An infective agent is not found but aet iologically some of these lesions might be the result of a leucocytoclastic vasculitis of vasa vasora or periadventitial vessels. A final group of non specific vasculitides not fitting into any of the characteristic patterns d escribed accounts for the residue of vasculitides associated with HIV.