An efficient and expeditious synthesis of a novel 5H-naphth[1',2': 5,6][1,4]oxazino[2,3-b]quinoxalin-5-one and its unique inhibitory activity againsta panel of human cancer cell lines

Citation
F. Miyata et al., An efficient and expeditious synthesis of a novel 5H-naphth[1',2': 5,6][1,4]oxazino[2,3-b]quinoxalin-5-one and its unique inhibitory activity againsta panel of human cancer cell lines, HETEROCYCLE, 54(2), 2001, pp. 619
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
0385-5414 → ACNP
Volume
54
Issue
2
Year of publication
2001
Database
ISI
SICI code
0385-5414(20010201)54:2<619:AEAESO>2.0.ZU;2-9
Abstract
The title compound (1) was efficiently synthesized in two steps starting fr om 2,3-dichloroquinoxaline (2) and 1-amino-2-naphthol (3); the method invol ves cyclization of 2 with 3 and subsequent salcomine oxidation. The compoun d (1) showed unique inhibitory activity against a panel of human cancer cel l lines.